TrueBinding Clinical Trial, Phase 2a
TrueBinding Clinical Trial, Phase 2a
TrueBinding Clinical Trial, Phase 2a
- Sponsor: TrueBinding Inc.
- General Summary: TB006PD2101: A Phase 2a, Multicenter, Randomized, Double-Blind, Placebo- Controlled Study of the Safety and Efficacy of TB006 in Participants with Parkinson’s Disease
- The study will evaluate the IP (TB006) dose-related safety in participants with PD and its efficacy in improving participants’ motor symptoms.
- Study Product: TB006, disease-modifying monoclonal antibody targeting Galectin-3
- TB006 is an experimental, humanized monoclonal antibody. It targets a protein called galectin-3. Galactin-3 is being studied for its potential role in inflammation and the formation of amyloid plaques.
- Because TB006 addresses both protein aggregation and neuroinflammation—key drivers in the progression of both AD and PD—it is a promising candidate for treating Parkinson's
- TB006 aims to reduce neuroinflammation, prevent protein clumping, and protect dopamine-producing neurons, which would potentially lead to improved motor function and a slowing of disease progression
- IV Infusion: 1-2 hours of continuous IV
- Target Population: Adult participants aged 50 to 80 years with PD, with <5 years since initial PD diagnosis
- Length: ~32 weeks